Simon Stone's work in theatre includes Phaedra at the National Theatre, Mefistofele for Opera di Roma, Olivier Award-winning Yerma at the Young Vic then The Armory New York, Medea at Internationaal Theater Amsterdam then Brooklyn Academy of Music, Flight 49, Ibsenhuis and Husbands and Wives and at ITA (then Toneelgroep Amsterdam); Peer Gynt at Deutsches Schauspielhaus, Hamburg; Rocco and his Brothers at Munich Kammerspiele; Nestroy Prize-winning John GabrielBorkman, Hotel Strindberg and Komplizen at the Burgtheater Vienna; Unsere Zeit at the Residenztheater Munich; The Greek Trilogy at the Berliner Ensemble; Three Sisters and The Revenge Trilogy at the Odeon Paris; Thyestes and The Government Inspector at Belvoir, Sydney and the Malthouse, Melbourne; Angels in America and Three Sisters at Theater Basel; The Wild Duck at the Barbican, Perth Festival, Ibsen Festival Oslo, Belvoir, Sydney and the Malthouse, Melbourne; The Promise, Neighbourhood Watch, Miss Julie (as writer), Hamlet, Cat on a Hot Tin Roof, Death of a Salesman and Strange Interlude at Belvoir, Sydney; The Cherry Orchard at Melbourne Theatre Company; and Face to Face and Baal for Sydney Theatre Company. As Founder and Artistic Director of The Hayloft Project, productions include The Only Child, Spring Awakening, B.C., Platonov and The Suicide. Opera includes The Greek Passion, Lear and Medée at Salzburg Festival, Innocence at the Festival d'Aix-en-Provence, Finnish National Opera and Covent Garden, Die Tote Stadt at Theater Baseland Bavarian State Opera, Lucia di Lammermoor at the Metropolitan Opera New York and Los Angeles Opera, La traviata at the Paris Opera, Wozzeck at the Vienna State Opera, and The Devils of Loudon at Bavarian State Opera.
Film includes The Dig and The Daughter.